Summary: Discover the living web of systems theory in biology, ecology, and humanity through this insightful exploration of life’s interconnected processes. Drawing from Ludwig von Bertalanffy’s foundational concepts and modern perspectives like Fritjof Capra and Pier Luigi Luisi’s The Systems View of Life, this article unravels how open systems drive metabolism, growth, and cognition in organisms, sustain Earth’s homeostasis as a living entity, and shape dynamic human organizations. From autopoiesis and dissipative structures to organizational resilience, learn how patterns, structures, and processes unify life across scales. Updated with contemporary sources like Meadows’ Thinking in Systems and Lenton’s Gaia research, this study bridges biology, ecology, and social science offering a holistic framework for understanding existence. Perfect for researchers, students, and professionals interested in systems thinking, organizational behavior, and ecological dynamics.